René Dubos: unearthing antibiotics

René J. Dubos, 1940

René Jules Dubos.

Mechanisms of Antibiotic Resistance in the Microbial World

EHRLICH was followed by Alexander FLEMING, who discovered penicillin by accident in 1928. Then, in the 1935, Gerhard DOMAGK discovered the sulfa drugs, thereby paving the way to the discovery of the anti-TB drug Isoniazid. Then, in 1939, René DUBOS became the first scientist to discover an antibiotic after purposely looking for it in soil microbes. DUBOS discovered Gramicidin, which is still us...

René Dubos, tuberculosis, and the “ecological facets of virulence”

Reflecting on his scientific career toward the end of his life, the French-educated medical researcher René Dubos presented his flowering as an ecological thinker as a story of linear progression-the inevitable product of the intellectual seeds planted in his youth. But how much store should we set by Dubos's account of his ecological journey? Resisting retrospective biographical readings, this...

René Dubos and Jared Diamond dream of Dutch polders.

The Author 2006. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved. doi:10.1093/eurpub/ckl122 Advance Access published on September 8, 2006 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....